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Anti -Sin3b Rabbit pAb

货号:GB11927

品牌:Servicebio

价格:¥500

规格: 100 μl

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Product Information

 

Description
Sin3b rabbit polyclonal
Protein full name

Paired amphipathic helix protein Sin3b

Synonyms

Sin3b, SIN3B, Paired amphipathic helix protein Sin3b, SIN3 transcription regulator family member B

Immunogen

Recombinant protein corresponding to Mouse Sin3b

Isotype IgG
Purity Affinity purification
Subcellular location

Nucleus

Uniprot ID

Q62141

 


 

Applications

 

Applications

IHC

IF

Species

Mouse, Rat

Mouse, Rat

Dilution

1: 500-1: 1000

1: 250-1: 500

Positive tissue

testis, placenta

testis, placenta

 


 

Background

 

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. 
 


 

Images

 

Immunohistochemistry analysis of paraffin-embedded mouse testis using Sin3b (GB11927) at dilution of 1: 1000

   

Immunohistochemistry analysis of paraffin-embedded mouse placenta using Sin3b (GB11927) at dilution of 1: 1000

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

 

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